Dynamic Light Scattering Instrument:
Litesizer DLS
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- +6
- 360°
- Particle size measurements from the nanometer to the micrometer range
- DLS back scatter detection ensures broad concentration range
- Automatic measurement modes
- Continuous transmittance measurement
The Litesizer DLS series characterizes nanoparticles and microparticles at the touch of a button. With these dynamic light scattering instruments, you can determine particles in dispersion and peptides or macromolecules in solution over a broad concentration range, which reduces your sample preparation time.
Key features
Benefit from the perfect angle choice – whatever your sample
- Ensure high resolution of different size populations via multi-angle particle sizing (MAPS)
- Choose from three detection angles (side, back, or forward scattering) for optimal parameter settings
- Manually select the most appropriate angle for your dynamic light scattering instrument or use automatic angle selection
- Benefit from the versatile back scattering angle, which is ideal for turbid samples as it reduces multiple scattering events and ensures optimal data quality
Rely on our cmPALS technique for zeta potential measurements
- Perform zeta potential measurements via electrophoretic light scattering with Litesizer DLS 700 and Litesizer DLS 500
- Conduct highly sensitive measurements at low sample concentrations (down to 0.1 mg/mL) with our patented cmPALS technique (European Patent 2 735 870)
- Enjoy shorter measuring times and minimal sample degradation with cmPALS
- Get highly reproducible zeta potential measurements with our unique Ω-shaped capillary of the zeta potential cuvettes
Stay flexible with the particle concentration measurement mode
- Perform calibration-free particle concentration measurements of up to three different size populations present within one sample with Litesizer DLS 700
- Use this mode based on single angle DLS or multi-angle particle sizing (MAPS) to ensure the applicability to monodisperse and polydisperse samples over a wide concentration range
Get continuous transmittance measurements for sample monitoring
- Enjoy instant feedback on your sample – the dynamic light scattering instruments continuously measure transmittance
- Take advantage of automatic optimization of measurement parameters (e.g., measurement angle, focus position, duration)
- Access information about the onset of sedimentation or aggregation within a series measurement
Determine refractive index with the same instrument
- Measure refractive index of the solvent at the exact wavelength and temperature of DLS or ELS measurements (European Patent 3 023 770) with Litesizer DLS 700 and Litesizer DLS 500
- Ensure maximum accuracy of particle size and zeta potential results under all experimental conditions
- Determine the refractive index within ±0.5 % with Litesizer DLS 700 and Litesizer DLS 500
Control your measurements with just a few clicks
- Manage data with Kalliope, our user-friendly, particle sizing software
- Know your input parameters, measurement signals, and results at a glance with our unique one-page workflow
- Quickly see your measurement results thanks to predefined standard reports and structured result overviews
- Take a deep dive into your data with an analysis function, Excel export, and customizable report templates
- Comply with 21 CFR Part 11
Technical specifications
| Litesizer DLS 700 | Litesizer DLS 500 | Litesizer DLS 100 | ||
| Particle size specifications | ||||
| Measurement principle | Dynamic Light Scattering (DLS) | |||
| Measuring range | 0.3 nm to 10 μm (particle diameter) | |||
| Measurement angles | 15°, 90°, 175°, Multi-angle particle sizing (MAPS) | 15°, 90°, 175° | 175° | |
| Min. concentration | 0.1 mg/mL (lysozyme) lower than 0.00001 % (0.1 ppm, Latex 100 nm) | 0.1 mg/mL (lysozyme) | ||
| Max. concentration | 50 % w/v (sample-dependent) | |||
| Min. sample volume | 12 µL | |||
| Accuracy | Better than +/-2 % on NIST traceable standards | |||
| Repeatability | Better than +/-2 % on NIST traceable standards | |||
| Particle Concentration Specifications | ||||
| Analysis model | Mie Theory | - | - | |
| Measuring range | 108 - 1013 particles/mL (sample dependent) | - | - | |
| Size limit | 1 µm | - | - | |
| Measurement angles | 15°, 90°, 175°, Multi-angle particle sizing (MAPS) | - | - | |
| Min. sample volume | 12 µL | - | - | |
| Accuracy | +/- 10 % (sample dependent) | - | - | |
| Repeatability | +/- 5 % (sample dependent) | - | - | |
| Zeta potential specifications | ||||
| Measuring principle | Electrophoretic Light Scattering (ELS) / cmPALS | - | ||
| Measuring range | >= +/-1000 mV | - | ||
| Mobility range | 10 -11 m²/V.s to 2 x 10 -7 m²/V.s | - | ||
| Size range | 3.8 nm to 100 µm (diameter) | - | ||
| Min. sample concentration | 0.1 mg/mL (lysozyme) | - | ||
| Max. sample concentration | 70 %w/v (sample-dependent) | - | ||
| Max. sample conductivity | 200 mS/cm | - | ||
| Min. sample volume | 50 µL (sample-viscosity-dependent) | - | ||
| Accuracy | Better than +/-10 % | - | ||
| Repeatability | +/-3 % | - | ||
| Molecular mass specifications | ||||
| Measuring principle | Static Light Scattering (SLS) | - | ||
| Measuring range (mass) | 300 Da to 20 MDa | - | ||
| Measuring range (particle size) | Up to 40 nm (diameter) | - | ||
| Measurement angle | 90° | - | ||
| Min. sample concentration | 0.1 mg/mL (lysozyme) | - | ||
| Accuracy | +/-10 % | - | ||
| Repeatability | +/-5 % | - | ||
| Transmittance specifications | ||||
| Measuring range | 0 % to 100 % | |||
| Min. sample volume | 15 µL | |||
| Accuracy | Better than +/-1 % | |||
| Refractive index specifications | ||||
| Measuring range | 1.28 to 1.50 | - | ||
| Min. sample volume | 1 mL | - | ||
| Accuracy | +/-0.5 % | - | ||
| General specifications | ||||
| Light source | Semiconductor laser diode / 40 mW, 658 nm | |||
| Laser warm-up time | 6 min | |||
| Temperature control range | 0 °C to 90 °C | |||
| Ambient operating temperature | 10 °C to 35 °C | |||
| Humidity | Up to 80 % non-condensing | |||
| Dimensions (W, D, H) | 460 mm, 485 mm, 135 mm | |||
| Weight | Approx. 18 kg (40 lb) | Approx. 16.3 kg (36 lb) | ||
Standards
ASTM
ISO
US Pharmacopoeia (USP)
Anton Paar Certified Service
- More than 350 manufacturer-certified technical experts worldwide
- Qualified support in your local language
- Protection for your investment throughout its lifecycle
- 3-year warranty
Documents
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An Insight into Multi-Angle Particle Sizing (MAPS) Application Reports
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An Insight into Particle Concentration Measurements Application Reports
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Black and green: catalyst and membranes for fuel cells Application Reports
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Characterization of Exosomes Isolated from Cell Culture Media Application Reports
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Characterizing different Formulations of Intimate Soap Application Reports
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Coenzyme Q10 - Organic Nanoparticle Characterization Application Reports
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Droplet Size Matters: Bioavailability of CBD Emulsions Application Reports
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Dynamic Light Scattering Measurements on Latex Standards with the Litesizer 500 Application Reports
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Dynamic streaming potential analysis Episode 1: Application in textile care Application Reports
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E-Book - Field Guide to Battery Materials Characterization – Revised and Updated Application Reports
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Emulsions for IV Application - Particle Size by DLS Application Reports
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Equal to the Task: Particle Size Measurements in Different Cuvettes Application Reports
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Fits Like a Glove: Particle Characterization for Latex Glove Production Application Reports
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Food Characterization Application Reports
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From Pottery to Membranes: Characterization of Ceramic Powders and Surfaces Application Reports
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Functionalized Foils in Food Packaging: A Surface Analysis Application Reports
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If you do not find the item you require, please contact your Anton Paar sales representative.
To find out if you can purchase online from your location, check the online availability below.
O-RING FOR MEASUREMENT FRAME LIQUID FLOW DISPERSION UNIT
Litesizer DLS 100 | 500 | 700
SYRINGES 2 ml LUER (100 pcs.)
Litesizer DLS 100 | 500
SAMPLE AND CLEANING KIT
Litesizer DLS 100 | 500 | 700
SYRINGES 5 ml LUER (100 pcs.)
Litesizer DLS 100 | 500
LOW-VOL. DISPOSABLE CUVETTE SET (Uvette)
Litesizer DLS 100 | 500 | 700
HOSE 2x4 SILICONE
Litesizer DLS 100 | 500
OMEGA CUVETTE FOR ZETA & SIZE (10 pcs.)
Litesizer DLS 100 | 500 | 700
O-RING 25x2 EPDM 70
Litesizer DLS 100 | 500
BUFFER SOLUTION PH4.01 HAMILTON
Litesizer DLS 100 | 500 | 700
VIAL 45 mL GLASS (100 Pcs.)
Litesizer DLS 100 | 500
BUFFER SOLUTION PH7.00 HAMILTON
Litesizer DLS 100 | 500 | 700
QUARTZ CUVETTE 12.5 x 12.5 x 45 mm
Litesizer DLS 100 | 500
PH STORAGE SOLUTION 500ML HAMILTON
Litesizer DLS 100 | 500 | 700
DISPOSABLE CUVETTE PS 10 x 10 x 45 mm 1 pack with 100 pcs
Litesizer DLS 100 | 500 | 700
DISPOSABLE CUVETTE LIDS 1 PACK OF 100 PIECES
Litesizer DLS 100 | 500 | 700
BUFFER SOLUTION PH10.01 HAMILTON
Litesizer DLS 100 | 500 | 700
SYRINGE FILTER ANOTOP TYPE 25
Litesizer DLS 100 | 500 | 700
GLASS CUVETTE 12.5 x 12.5 x 45 mm
Litesizer DLS 100 | 500
SYRINGE FILTER ANOTOP TYPE 10
Litesizer DLS 100 | 500 | 700
LOW VOLUME CUVETTE QUARTZ 45 µl 12.5 x 12.5 x 45 mm
Litesizer DLS 100 | 500 | 700
ZETA POTENTIAL CONTROL
Litesizer DLS 500
100 nm NIST TRACEABLE SIZE STANDARD
Litesizer DLS 100 | 500 | 700
HOSE 1x2 SILICONE
Litesizer DLS 500
220 nm NIST TRACEABLE STANDARD 0.002 %
Litesizer DLS 100 | 500 | 700
Dosing System
Litesizer DLS 500
- Accessory for Litesizer 500
- Automatically modifies the pH or adds solvents – saving time, and eliminating human error
- Use pH ramp templates in the software to set up your experiments
- Self-cleaning, no risk of sample carryover
USB CABLE
Litesizer DLS 100 | 500 | 700
Software for particle analysis:
Kalliope
Litesizer DLS 100 | 500 | 700
- Particle analysis software for the Litesizer DLS Series, PSA Series, and Litesizer DIA 500
- Start your particle measurements in just three clicks
- One-page workflow user interface
- Live monitoring of measurement results, analysis function, customizable reporting, and multiple exporting capabilities
The Dynamic and Electrophoretic Light Scattering Guide
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